Expanding Donor Heart Utilization Through Machine Perfusion Technologies

Abstract Purpose of Review Recent advances in donor heart preservation have allowed the utilization hearts that would typically be discarded due to prolonged ischemic times or donation via circulatory death pathway. This review will discuss recent including optimization machine perfusion technologies and future strategies potential benefit for transplant outcomes. Findings Improvements organ enabled retrieval were not ideal static cold storage. Machine (normothermic hypothermic) normothermic regional ultimately expanded pool adult transplantation. Xenotransplantation has also incorporated porcine preservation. Summary Traditional storage is feasible non-complex donors transplants. increased however optimal are dependent on criteria, predicted surgical complexity.